Work

Using LC-MS/MS Metabolomics to Study Cancer Metabolism

Year: 2020

Type: article

Abstract: Using LC-MS/MS, we found that pancreatic cancer proliferation can be slowed down using the drug Brequinar as a DHODH inhibitor, which reduces the number of metabolites necessary to create pyrimidines and allow proliferation.

Source: Graduate Medical Education Research Journal

Authors: Robertson, Troy, Dawkins, Marshall, Mullen, Nick, Singh, Pankaj

Institutions: Prairie View A&M University, Nebraska Wesleyan University, University of Nebraska Medical Center

Language: English

Topic: Metabolomics and Mass Spectrometry Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3046484987

FWCI:

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Related to: 20