Work

Pan-resistant Candida auris: New York subcluster susceptible to antifungal combinations

Year: 2020

Type: article

Abstract: Four pan-resistant Candia auris strains from New York outbreak were 100% inhibited in vitro by combinations of two antifungal drugs using fixed concentrations achievable in vivo . Pan-resistant C. auris strains have mutations in eleven gene targets associated with major antifungal drugs, and constituted a distinct sub-cluster among NY strains.

Source: The Lancet Microbe

DOI: 10.1016/s2666-5247(20)30090-2

Authors: Brittany O'Brien, Jiali Liang, Sudha Chaturvedi, Jonathan L Jacobs, Vishnu Chaturvedi

Institutions: New York State Department of Health, Wadsworth Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $7,280