Work

Adaptable DNA interactions regulate surface triggered self assembly

Year: 2020

Type: article

Abstract: DNA-mediated multivalent interactions between colloidal particles have been extensively applied for their ability to program bulk phase behaviour and dynamic processes. Exploiting the competition between different types of DNA-DNA bonds, here we experimentally demonstrate the selective triggering of colloidal self-assembly in the presence of a functionalised surface, which induces changes in particle-particle interactions. Besides its relevance to the manufacturing of layered materials with controlled thickness, the intrinsic signal-amplification features of the proposed interaction scheme make it valuable for biosensing applications.

Source: Nanoscale

DOI: 10.1039/d0nr04461j

Authors: Roberta Lanfranco, Pritam Kumar Jana, Gilles Bruylants, Pietro Cicuta, Bortolo Matteo Mognetti, Lorenzo Di Michele

Institutions: University of Cambridge, Université Libre de Bruxelles, Nanosystem (Russia), Imperial College London

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid