Work

Circ_0016418 promotes melanoma development and glutamine catabolism by regulating the miR-605-5p/GLS axis.

Year: 2020

Type: article

Abstract: BACKGROUND: Malignant melanoma is a skin cancer with a high rate of metastasis. Numerous circular RNAs (circRNAs) have been shown to play vital roles in melanoma. This research aimed to investigate the role and molecular basis of circ_0016418 in melanoma progression. METHODS: . RESULTS: . CONCLUSION: Knockdown of circ_0016418 suppressed melanoma development and glutamine catabolism by modulating the miR-605-5p/GLS pathway.

Source: PubMed

Authors: Ruijuan Lu, Xusheng Zhang, Xiaojuan Li, Xuefeng Wan

Institutions: Northwest Minzu University, First Affiliated Hospital of Xinjiang Medical University

Language: English

Topic: Circular RNAs in diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3049226851

FWCI: 0.785

Cites: 34

Cited by: 17

Related to: 10