Mechanism of Myeloid-derived Suppressor Cell Accumulation in Cancer and Susceptibility to Reversal by Sunitinib
Year: 2009
Type: article
Abstract: Overview: Myeloid-derived suppressor cells in cancer: a novel therapeutic target. Immunotherapy in cancerMyeloid-derived suppressor cells limit immunotherapy Myeloid-derived suppressor cells limit anti-angiogenic therapy Multiple factors are implicated in MDSC formation Vascular Endothelial Growth Factor Stem Cell Factor Granulocyte-and Granulocyte/Monocyte Colony Stimulating Factors S100A9 and Inflammation Intracellular signaling implicated in MDSC programming 4 Chapter 2: Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
Author: Jennifer S. Ko
Institution: Case Western Reserve University
Language: English
Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W30541128