Charge required to induce a seizure during initial dose titration using right unilateral brief pulse electroconvulsive therapy
Year: 2020
Type: article
Abstract: Minimizing cognitive side effects of electroconvulsive therapy (ECT) while maintaining clinical efficacy is a key challenge. Given that the electrical charge required to induce a seizure varies by as much as 30-fold among patients [1], and that clinical efficacy and side effects of ECT depend strongly on the dose applied relative to the individual seizure threshold [2], many providers have adopted routine seizure threshold determination at the time of first treatment. As these protocols are not standardized, and likely vary based on the ECT electrode placement and stimulus parameters, information about the typical seizure threshold would help guide clinical practice.
Source: Brain stimulation
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,750
Awards: Fostering Research Mentorship and Training During Psychiatry Residency, Machine learning for data-driven subtyping of major depression, A Transdiagnostic Assessment of Electroconvulsive Therapy Modulation of Anhedonia and Reward circuitry: Targets, Biomarkers and Predictors of Response, Dysregulation of Appetitive & Aversive Amygdala Circuits in Bipolar Disorder
OpenAlex ID: W3055030714