Work

Recent advances in topical carriers of anti-fungal agents

Year: 2020

Type: review

Abstract: Fungal skin infections are the most common global issue for skin health. Fungal infections are often treated by topical or systemic anti-fungal therapy. Topical fungal therapy is usually preferred because of their targeted therapy and fewer side effects. Advanced topical carriers because of their distinct structural and functional features, overcome biopharmaceutical challenges associated with conventional drug delivery systems like poor retention and low bioavailability. Literature evidence indicated topical nanocarriers loaded with anti-fungal agents display superior therapeutic response with minimum toxicity. Nanocarriers often used for topical anti-fungal medication includes Solid-Lipid nanoparticles, Microemulsions, Liposomes, Niosomes, Microsponge, Nanogel, Nanoemulsion, Micelles etc. This review summarizes recent advances in novel strategies employed in topical carriers to improve the therapeutic performance of anti-fungal drugs.

Source: Heliyon

DOI: 10.1016/j.heliyon.2020.e04663

Authors: Abhinava Garg, Ganti S. Sharma, Amit K. Goyal, Goutam Ghosh, Sudam Chandra Si, Goutam Rath

Institutions: Indo Soviet Friendship College of Pharmacy, Central University of Rajasthan, Siksha O Anusandhan University

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,750