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Difficulties maintaining prolonged fixation and attention-deficit/hyperactivity symptoms share genetic influences in childhood

Year: 2020
Type: article
Study design: Observational Study
Abstract: This study investigated the association between the ability to maintain prolonged (2-minute) fixation on a visual target and ADHD traits in a sample consisting of 120 monozygotic and 120 dizygotic twin pairs, aged 9 to 14 years. More intrusive saccades during the task was associated with higher level of parent-reported ADHD traits. Both intrusive saccades and ADHD symptoms had high heritability estimates, and there was a moderate genetic correlation between number of intrusive saccades and ADHD. This study suggests that inability to maintain ocular fixation for longer times is etiologically linked to ADHD traits in the general population.
DOI: 10.1016/j.psychres.2020.113384
Authors: Terje Falck-Ytter, Erik Pettersson, Sven Bölte, Brian D'Onofrio, Paul Lichtenstein, Daniel P. Kennedy
Institutions: Uppsala University, Swedish Collegium for Advanced Study, Karolinska Institutet, Curtin University, Region Stockholm, Indiana University Bloomington, Indiana University
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $2,900
Awards: G1658766036, UNFOLDING AUTISM AND ADHD: CONVERGENT AND DIVERGENT PATHWAYS IN INFANTS AT RISK, G1769301718, G2227736344, The role of gut microbiota in typical and atypical brain development, G3507817600, Genes, environments and the development of mental health and behavior problems from childhood to adulthood, G712881263
OpenAlex ID: W3067894144
FWCI: 0.55
Cites: 17
Cited by: 12
Related to: 10