Work

Microbe-Metabolite Associations Linked to the Rebounding Murine Gut Microbiome Postcolonization with Vancomycin-Resistant Enterococcus faecium

Year: 2020

Type: article

Abstract: This study demonstrates the importance and power of linking bacterial composition profiling with metabolomics to find the interactions between commensal gut bacteria and a specific pathogen. Knowledge from this research will inform gut microbiome engineering strategies, with the aim of translating observations from animal models to human-relevant therapeutic applications.

Source: mSystems

DOI: 10.1128/msystems.00452-20

Authors: Andre Mu, Glen P. Carter, Lucy Li, Nicole S. Isles, Alison F. Vrbanac, James T. Morton, Alan K. Jarmusch, David P. De Souza, Vinod K. Narayana, Komal Kanojia, Brunda Nijagal, Malcolm J. McConville, Rob Knight, Benjamin P. Howden, Timothy P. Stinear

Institutions: The University of Melbourne, Peter Doherty Institute, University of California San Diego, Flatiron Institute, Peter MacCallum Cancer Centre

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,500

Funders: University of California, San Diego, Medical Research Council, National Health and Medical Research Council, National Medical Research Council

Awards: Genomic approaches in human health microbiology, Understanding how Staphylococci Respond to Antibiotics

OpenAlex ID: W3072819463

FWCI: 0.325

Cites: 32

Cited by: 11

Related to: 10