Work

Emerging Organometallic Methods for the Synthesis of C‐Branched (Hetero)aryl, Alkenyl, and Alkyl Glycosides: C−H Functionalization and Dual Photoredox Approaches

Year: 2020

Type: review

Abstract: Transition-metal-catalyzed C-H functionalization and photoredox nickel dual catalysis have emerged as innovative and powerful avenues for the synthesis of C-branched glycosides. These two concepts have been recently established and provide efficient and mild methods for accessing a series of valuable complex C-branched glycosides of great interest. Herein, recent developments in the synthesis of C-branched aryl/alkenyl/alkyl glycosides through these two approaches are highlighted.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.202003267

Authors: Juba Ghouilem, Morgane de Robichon, Franck Le Bideau, Angélique Ferry, Samir Messaoudi

Institutions: Centre National de la Recherche Scientifique, Université Paris-Saclay, Biomolécules : Conception, Isolement, Synthèse, CY Cergy Paris Université

Language: English

Topic: Catalytic C–H Functionalization Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Agence Nationale de la Recherche

Awards: Access to C-glycosides by directed metal-catalyzed C-H functionalization at the anomeric position., On demand Selective Functionalization of Sugar C(sp3)–H bonds Using a Transient Directing Group (TDG) strategy