Year: 2020
Type: article
Abstract: As part of the 2019 Immunotherapy Bridge congress (December 4-5, Naples, Italy), the Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were the use of chimeric antigen receptor T cell therapy in solid tumors, whether the Immunoscore should be more widely used in clinical practice, whether antibody-dependent cellular cytotoxicity is important in the mode of action of anticytotoxic T-lymphocyte-associated protein 4 antibodies, whether the brain is immunologically unique or just another organ, the role of microbiome versus nutrition in affecting responses to immunotherapy, and whether chemotherapy is immunostimulatory or immunosuppressive. Discussion of these important topics are summarized in this report.
Institutions: Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Fondazione IRCCS Istituto Nazionale dei Tumori, Providence Portland Medical Center, Inserm, Centre de Recherche des Cordeliers, Laboratoire d’immunologie intégrative du cancer, Universitätsklinikum Tübingen, University of Tübingen, Georgetown University, Georgetown University Medical Center, Georgetown Lombardi Comprehensive Cancer Center, The University of Texas MD Anderson Cancer Center, Roswell Park Comprehensive Cancer Center, University of California, San Francisco, Parker Institute for Cancer Immunotherapy, Medical University of South Carolina, MUSC Hollings Cancer Center, University College Hospital, University College London Hospitals NHS Foundation Trust, University College London, University of California, Los Angeles, California State University Los Angeles, UCLA Medical Center, National Institutes of Health, National Cancer Institute, Center for Cancer Research
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,490
Funder: Cancer Research UK
Awards: G6229580388, G721865983
OpenAlex ID: W3080152226