Work

RAS and RHO family GTPase mutations in cancer: twin sons of different mothers?

Year: 2020

Type: review

Source: Critical Reviews in Biochemistry and Molecular Biology

DOI: 10.1080/10409238.2020.1810622

Authors: Richard G. Hodge, Antje Schaefer, Sarah V. Howard, Channing J. Der

Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: U.S. Department of Defense, American Association for Cancer Research, Lustgarten Foundation, National Institutes of Health, National Cancer Institute

Awards: G2221353213, Stromal Fibroblast Autophagy In Tumor Progression and Desmoplasia, Biological Activity of Ras Oncogenes, Defining RAS isoform- and mutation-specific roles in oncogenesis, Mechanisms of PAK1 activation, signaling and tumor resistance, G3371121024, G3744773358, Targeting undruggable RAS for cancer treatment, Washington University SPORE in Pancreatic Cancer, G5028106406, ERK inhibitor resistance and ERK isoform-dependent growth in pancreatic cancer, G6517443003, Identification of synthetic lethal interactors in pancreatic cancer, TARGETING KRAS FOR PANCREATIC CANCER TREATMENT

OpenAlex ID: W3081158222

FWCI: 0.756

Cites: 140

Cited by: 49

Related to: 10