Year: 2007
Type: dissertation
Abstract: A gallamine-tacrine dimer and related analogues are presented. These compounds act as dual-mode cholinesterase inhibitors and additionally as allosteric modulators of muscarinic M2 receptors. Next to their synthesis, detailed kinetic and docking investigations are described to characterize these highly potent compounds.
Source: bonndoc (University of Bonn)
Author: Paul W. Elsinghorst
Language: English
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3082793097