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Optimal drug therapies for HIV in pregnant women and in children: Considering pharmacogenetics, drug-drug interactions and formulations

Year: 2018

Type: article

Abstract: Optimal ART in children and pregnant women lags behind that of nonpregnant adults. While establishing safety and efficacy in these subpopulations is important, the efficient implementation of pharmacokinetic studies confirming appropriate dosing is key. Pharmacogenetic variants, drug-drug interactions and formulation are sources of pharmacokinetic variability for which a priori adjustment of doses would be optimal. Suitable age-appropriate formulations are essential at an early stage.

Source: Proceedings for Annual Meeting of The Japanese Pharmacological Society

DOI: 10.1254/jpssuppl.wcp2018.0_sy81-3

Author: Helen Mcilleron

Institution: University of Cape Town

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W3083920940

FWCI:

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