Transcriptomic and functional pathway features were associated with survival after pathological complete response to neoadjuvant chemotherapy in breast cancer.
Year: 2020
Type: article
Abstract: expressing tumors have significantly worse overall survival in TCGA BC cohort. We demonstrated the genes and functional pathway features associated with pCR and survival utilizing the bioinformatics approach to public BC cohorts. Some genes involved in recurrence after pCR due to NAC also served as prognostic factors in primary BC.
Source: PubMed Central
Institutions: Roswell Park Comprehensive Cancer Center, Lund University, Karolinska University Hospital, Karolinska Institutet, University of Miami, Nova Southeastern University, Holy Cross Hospital, Massachusetts General Hospital, Fukushima Medical University, Tokyo Medical University, University at Buffalo, State University of New York, Niigata University, Yokohama City University
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
Funder: National Cancer Institute
OpenAlex ID: W3085516345