Consensus Recommendations on the Use of18F-FDG PET/CT in Lung Disease
Year: 2020
Type: article
Abstract: PET with 18F-FDG has been increasingly applied, predominantly in the research setting, to study drug effects and pulmonary biology and to monitor disease progression and treatment outcomes in lung diseases that interfere with gas exchange through alterations of the pulmonary parenchyma, airways, or vasculature. To date, however, there are no widely accepted standard acquisition protocols or imaging data analysis methods for pulmonary 18F-FDG PET/CT in these diseases, resulting in disparate approaches. Hence, comparison of data across the literature is challenging. To help harmonize the acquisition and analysis and promote reproducibility, we collated details of acquisition protocols and analysis methods from 7 PET centers. From this information and our discussions, we reached the consensus recommendations given here on patient preparation, choice of dynamic versus static imaging, image reconstruction, and image analysis reporting.
Source: Journal of Nuclear Medicine
Authors: Delphine L. Chen, Safia Ballout, Laigao Chen, Joseph Cheriyan, Gourab Choudhury, Ana M. Denis-Bacelar, Elise Emond, Kjell Erlandsson, Marie Fisk, Francesco Fraioli, Ashley M. Groves, Roger N. Gunn, Jun Hatazawa, Beverley F. Holman, Brian F. Hutton, Hidehiro Iida, Sarah Lee, William MacNee, Keiko Matsunaga, Divya Mohan, David Parr, Alaleh Rashidnasab, Gaia Rizzo, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Nicola Tregay, Edwin J.R. van Beek, Laurence Vass, Marcos F. Vidal Melo, Jeremy W. Wellen, Ian Wilkinson, Frederick J. Wilson, Tilo Winkler
Institutions: Seattle Cancer Care Alliance, University of Washington, University of Leeds, Pfizer (United States), University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, The Queen's Medical Research Institute, University of Edinburgh, National Physical Laboratory, University College London, Invicro (United Kingdom), Imperial College London, The University of Osaka, The Royal Free Hospital, University of Turku, Turku PET Centre, GlaxoSmithKline (United States), University Hospitals Coventry and Warwickshire NHS Trust, Derby Hospitals NHS Foundation Trust, Harvard University, Massachusetts General Hospital, Celgene (United States), GlaxoSmithKline (United Kingdom)
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: Pfizer, GlaxoSmithKline, Society of Nuclear Medicine and Molecular Imaging, Celgene, National Institute for Health and Care Research, University College London, Miljø- og Fødevareministeriet, Siemens Healthineers, National Institutes of Health, Genentech, Japan Society for the Promotion of Science, National Physical Laboratory, National Heart, Lung, and Blood Institute, National Institute of Biomedical Imaging and Bioengineering
Awards: PET/CT-Guided Personalized Mechanical Ventilation to Minimize Ventilator-Induced Lung Injury, Evaluation of anti-cancer drug delivery by means of positron emission tomography: a proposal for new strategy of cancer treatment, PET IMAGING CCR2 IN LUNG INFLAMMATION, POSITRON EMISSION TOMOGRAPHIC IMAGING OF LUNG TRANSPLANT, G9000126234, The PET Radiotracer Translation and Resource Center (PET-RTRC)
OpenAlex ID: W3087224375