Work

Frequency-dependent spike-pattern changes in motor cortex during thalamic deep brain stimulation

Year: 2020

Type: article

Abstract: The network mechanisms of thalamic deep brain stimulation (DBS) are not well understood at the cellular level. This study investigated the neuronal firing rate and pattern changes in the motor cortex resulting from stimulation of the cerebellar-receiving area of the motor thalamus. We showed that there is a nonintuitive relationship between general entropy-based spike-pattern measures and phase-locked regularization to DBS.

Source: Journal of Neurophysiology

DOI: 10.1152/jn.00198.2020

Authors: Edward M. Bello, Filippo Agnesi, Yizi Xiao, Joan Dao, Matthew D. Johnson

Institution: University of Minnesota

Language: English

Topic: Neurological disorders and treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering