Early life RSV infection in neonatal mice leads to exacerbated allergic asthma due to persistent Th2 pulmonary responses that are abrogated by maternal supplementation with a L. johnsonii probiotic
Year: 2020
Type: article
Abstract: The development of immune responses in infants is central to establishing a balanced system that reacts appropriately to infectious stimuli but does not induce altered disease states with potential long term sequelae. Studies have linked severe RSV infection during early-life with an enhanced likelihood of developing childhood asthma.
Institution: University of Michigan
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,300
OpenAlex ID: W3088757403
