Year: 2020
Type: article
Abstract: : The ongoing biomedical nanotechnology has intrigued increasingly intense interests in cerium oxide nanoparticles, ceria nanoparticles or nano-ceria (CeO 2 -NPs). Their remarkable vacancy-oxygen defect (VO) facilitates the redox process and catalytic activity. The verification has illustrated that CeO 2 -NPs, a nanozyme based on inorganic nanoparticles, can achieve the anti-inflammatory effect, cancer resistance, and angiogenesis. Also, they can well complement other materials in tissue engineering (TE). Pertinent to the properties of CeO 2 -NPs and the pragmatic biosynthesis methods, this review will emphasize the recent application of CeO 2 -NPs to orthopedic biomedicine, in particular, the bone tissue engineering (BTE). The presentation, assessment, and outlook of the orthopedic potential and shortcomings of CeO 2 -NPs in this review expect to provide reference values for the future research and development of therapeutic agents based on CeO 2 -NPs. Keywords: CeO 2 -NPs, green synthesis, ROS, bone tissue engineering, coating, orthopedic implants
DOI: 10.2147/ijn.s270229
Authors: Hongru Li, Peng Xia, Su Pan, Zhiping Qi, Chuan Fu, Ziyuan Yu, Weijian Kong, Yuxin Chang, Kai Wang, Dankai Wu, Xiaoyu Yang
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,836
OpenAlex ID: W3088989128