Year: 2020
Type: article
Abstract: At 1 year, 45% of severe asthma change molecular phenotype as determined by sputum transcriptomic analysis. Together with concomitant shift in sputum granulocytic markers, this may indicate variability of driving mechanisms in this unstable group.https://bit.ly/35aj489
Source: European Respiratory Journal
Authors: Nazanin Z. Kermani, Stelios Pavlidis, Jiaxing Xie, Kai Sun, Matthew Loza, Fred Baribaud, Steve J. Fowler, Dominic E. Shaw, Louise J. Fleming, Peter H. Howarth, Ana R. Sousa, Julie Corfield, Charles Auffray, Bertrand De Meulder, Peter J. Sterk, Yike Guo, Mohib Uddin, Ratko Djukanovic, Ian M. Adcock, Kian Fan Chung
Institutions: Imperial College London, Royal Brompton & Harefield NHS Foundation Trust, Janssen (United Kingdom), University of Manchester, University of Nottingham, NIHR Southampton Respiratory Biomedical Research Unit, GlaxoSmithKline (United Kingdom), AstraZeneca (Sweden), Lyon 1 Université, Centre National de la Recherche Scientifique, Inserm, Amsterdam University Medical Centers, University of Amsterdam
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funder: Innovative Medicines Initiative
OpenAlex ID: W3089818913