Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
Year: 2020
Type: article
Source: Nature Biomedical Engineering
Authors: Marvin Krohn-Grimberghe, Michael J. Mitchell, Maximilian J. Schloss, Omar F. Khan, Gabriel Courties, Pedro P. G. Guimaraes, David Rohde, Sebastian Cremer, Piotr S. Kowalski, Yuan Sun, Mingchee Tan, Jamie Webster, Karin Wang, Yoshiko Iwamoto, Stephen P. Schmidt, Gregory R. Wojtkiewicz, Ribhu Nayar, Vanessa Frodermann, Maarten Hulsmans, Amanda Chung, Friedrich Felix Hoyer, Filip K. Swirski, Robert Langer, Daniel G. Anderson, Matthias Nahrendorf
Institutions: Harvard University, University of Freiburg, Massachusetts General Hospital, Universitäts-Herzzentrum Freiburg-Bad Krozingen, Center for Systems Biology, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, University of Pennsylvania, Universitätsklinikum Würzburg
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: U.S. Department of Health and Human Services, Prostate Cancer Foundation, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, European Commission, Deutsche Forschungsgemeinschaft, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Max-Planck-Gesellschaft, National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, Center for Information Technology
Awards: Controlled Release of Macromolecules, G1995861867, G2360436881, Targeting epigenetic REPROGRamming of innate immune cells in Atherosclerosis Management and other chronic inflammatory diseases, G2492496823, Interfering with the macrophage life cycle of atherosclerosis, G3250453925, G4599553043, G4774430914, G5029827730, G5147468995, Imaging organ system interfaces in ischemic heart disease, Cardiac MR and CT Research, G5797641063, G6632036768, Quantitative nanoparticle imaging of macrophages, Polymeric Nanoparticles for siRNA Delivery to Bone Marrow Endothelium to Disrupt Tumor Cell Adhesion and Bone Metastasis Formation In Vivo, G8200681001, G8536971979, G9000163483, G9000216863, Hematopoiesis in Cardiovascular Disease, Cancer Center Support (Core) Grant, G941982536
OpenAlex ID: W3090924548