Pathogen identification in culture-negative cerebrospinal fluid specimens of patients with purulent meningitis using next-generation sequencing technology.
Year: 2020
Type: article
Abstract: , each group with a different proportion of bacterial species. The results indicated that PM may result from infections by multiple bacterial species as opposed to a single species, with infectivity determined by abundance of the dominant species. Furthermore, Next-Generation Sequencing allowed a sensitive and specific etiological basis for identification of pathogens not only in the cerebrospinal fluid specimens, but also in other clinical samples.
Source: PubMed
Authors: Xin Men, Guige Zhao, Wei Zhao, Jianfei Zhang, Yuan Yang, Chao Chen
Institutions: Northwest University, Microbiology Institute of Shaanxi
Language: English
Subfield: Microbiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3091783706