Work

Ex Vivo Lung Perfusion: Current Achievements and Future Directions

Year: 2020

Type: review

Abstract: There is a severe shortage in the availability of donor organs for lung transplantation. Novel strategies are needed to optimize usage of available organs to address the growing global needs. Ex vivo lung perfusion has emerged as a powerful tool for the assessment, rehabilitation, and optimization of donor lungs before transplantation. In this review, we discuss the history of ex vivo lung perfusion, current evidence on its use for standard and extended criteria donors, and consider the exciting future opportunities that this technology provides for lung transplantation.

Source: Transplantation

DOI: 10.1097/tp.0000000000003483

Authors: Nikhil K. Prasad, Chetan Pasrija, Tara Talaie, Alexander S. Krupnick, Yunge Zhao, Christine L. Lau

Institution: University of Maryland, Baltimore

Language: English

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases