Work

Glycogen Metabolism: IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway (Adv. Sci. 19/2020)

Year: 2020

Type: article

Abstract: Little is known about how glycogen metabolism is manipulated during exercise. In article number 2001502, John Zhong Li, Tiemin Liu, Xingxing Kong, and coworkers identify that interferon regulatory factor 4 (IRF4) in skeletal muscle regulates glycogen metabolism and subsequent exercise capacity. This work reveals a regulatory pathway including IRF4/protein targeting to glycogen (PTG)/glycogen synthesis on controlling exercise capacity.

Source: Advanced Science

DOI: 10.1002/advs.202070108

Authors: Xiaopeng Zhu, Ting Yao, Ru Wang, Shanshan Guo, Xin Wang, Zhenqi Zhou, Yan Zhang, Xiaozhen Zhuo, Ruitao Wang, John Zhong Li, Tiemin Liu, Xingxing Kong

Language: English

Topic: Metabolism, Diabetes, and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,000

OpenAlex ID: W3092118647

FWCI:

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