Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile
Year: 2020
Type: article
Study design: Observational Study
Source: Modern Pathology
Authors: Krinio Giannikou, Zachary Zhu, Jaegil Kim, Kellen D. Winden, Magdalena E. Tyburczy, David Marron, Joel S. Parker, Zachary Hebert, Anika Bongaarts, Len Taing, Henry W. Long, William V. Pisano, Sanda Alexandrescu, Brianna Godlewski, Mark Nellist, Katarzyna Kotulska, Sergiusz Jozwiak, Marcin Roszkowski, Marek Mandera, Elizabeth A. Thiele, Hart Lidov, Gad Getz, Orrin Devinsky, Michael S. Lawrence, Keith L. Ligon, David W. Ellison, Mustafa Sahin, Eleonora Aronica, David M. Meredith, David J. Kwiatkowski
Institutions: Broad Institute, Brigham and Women's Hospital, Harvard University, Boston Children's Hospital, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Dana-Farber Cancer Institute, Amsterdam Neuroscience, Amsterdam University Medical Centers, University of Amsterdam, Erasmus MC, Medical University of Warsaw, Children's Memorial Health Institute, Medical University of Silesia, Massachusetts General Hospital, New York University, St. Jude Children's Research Hospital, Stichting Epilepsie Instellingen Nederland
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Award: G1819525301
OpenAlex ID: W3092527178