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Effect of Neoadjuvant Chemoradiotherapy on Pathologic Stage and Survival in Patients with Locally Advanced Esophageal Cancer

Year: 2016

Type: article

Abstract: Although esophageal cancer comprises a small percentage (1.5%) of total cancer cases in the United States, mortality rate remains high.In the United States, an estimated 16,980 cases of esophageal cancer will be diagnosed in 2015 and 15,590 deaths are expected from the disease [1,2].Regardless of histology, approximately 50-60% of patients present with incurable locally advance or metastatic disease.As such, at most 10-15% of all patients presenting with esophageal cancer are cured [3].For those with locally advanced, non-metastatic disease, cure is achieved in up to 40% of patients when multimodality therapy is used [4,5].

Source: Journal of Cancer Science and Clinical Oncology

DOI: 10.15744/2394-6520.3.105

Authors: Karapetyan L, Burtness B, Forastiere A, Heitmiller RF, Heath E, Gibson MK