Work

Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease

Year: 2020

Type: article

Abstract: T cell proliferation and reduced their population in the central nervous system while increasing them in the lung. This study supports noninvasive pulmonary particle delivery, such as inhalable administration, to treat autoimmune disease.

Source: Science Advances

DOI: 10.1126/sciadv.abc9317

Authors: Eiji Saito, Stephen J. Gurczynski, Kevin R. Kramer, Carol A. Wilke, Stephen D. Miller, Bethany B. Moore, Lonnie D. Shea

Institutions: University of Michigan, Michigan Medicine, Northwestern University

Language: English

Topic: Inhalation and Respiratory Drug Delivery

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Biomedical Imaging and Bioengineering

Awards: G1526487482, G301048564, G332175954, Antigen loaded particles for tolerance induction, G6311256826, Michigan Diabetes Research Center (MDRC)

OpenAlex ID: W3092989698

FWCI: 4.672

Cites: 45

Cited by: 59

Related to: 10