Work

Osteoclast differentiation by RANKL and OPG signaling pathways

Year: 2020

Type: review

Source: Journal of Bone and Mineral Metabolism

DOI: 10.1007/s00774-020-01162-6

Authors: Nobuyuki Udagawa, Masanori Koide, Midori Nakamura, Yuko Nakamichi, Teruhito Yamashita, Shunsuke Uehara, Yasuhiro Kobayashi, Yuriko Furuya, Hisataka Yasuda, Chie Fukuda, Eisuke Tsuda

Institutions: Matsumoto Dental University, Oriental Yeast Co., Ltd. (Japan), Daiichi-Sankyo (Japan)

Language: English

Topic: Bone Metabolism and Diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Japan Society for the Promotion of Science

Awards: Exploration of druggable targets for metabolic bone diseases using sensitive reporter systems and integrative proteogenomic approaches, Elucidation of the role of sclerostin in growth and development process of bone, Development of alveolar bone turnover control method based on Wnt signaling network, Development of bone anabolic drugs via evaluation of Wnt activity, Identification of regulators of bone regeneration using multiple modes of CRISPR-Cas9 genetic screens, Development of bioactive nanocarbon composite enabling spatial and temporal control of the metastatic bone cancer environment and biosafety assessments, Identification of transcriptional factors and tissue resident macrophages involved in stem cell differentiation., Elucidation of unknown network mechanism of osteoprotegerin in bone, cardiovascular and digestive system, Development of new therapeutic agents for bone and periodontal diseases based on the bone metabolism-uncoupling mechanisms, Anlysis of the RANKL-Siglec-15 signal molecular mechanism for alveolar bone regeneration

OpenAlex ID: W3093365748

FWCI: 6.644

Cites: 59

Cited by: 786

Related to: 10