Year: 2020
Type: review
Abstract: In many ways, cancer cells are different from healthy cells. A lot of tactical nano-based drug delivery systems are based on the difference between cancer and healthy cells. Currently, nanotechnology-based delivery systems are the most promising tool to deliver DNA-based products to cancer cells. This review aims to highlight the latest development in the lipids and polymeric nanocarrier for siRNA delivery to the cancer cells. It also provides the necessary information about siRNA development and its mechanism of action. Overall, this review gives us a clear picture of lipid and polymer-based drug delivery systems, which in the future could form the base to translate the basic siRNA biology into siRNA-based cancer therapies.
Source: Acta Pharmaceutica Sinica B
Institutions: Pontificia Universidad Católica de Chile, University of Ulster, Yarmouk University, Lovely Professional University, University of Technology Sydney, IMU University, Indian Institute of Technology Delhi, Gyan Vihar University, Shoolini University, Hunter Medical Research Institute, University of Newcastle Australia
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,600
Award: G2393391674
OpenAlex ID: W3093405310