Year: 2020
Type: review
Abstract: Ulcerative colitis (UC) is primarily a disease of non-smokers or ex-smokers. Since there have been previous claims of the beneficial effects of transdermal nicotine, researchers studied its efficacy to include it in the treatment regimen: to prevent remissions and as maintenance therapy. This review aims to evaluate the efficacy of transdermal nicotine as a treatment option for mild to moderately active ulcerative colitis. We shortlisted 22 articles after a careful analysis and elimination process. These articles were reviewed and analyzed, and it was found that transdermal nicotine in combination with conventional therapy was more beneficial than individual treatment with either. Further controlled studies evaluating the appropriate dosage for remission and maintenance treatment needs to be done.
Source: Cureus
DOI: 10.7759/cureus.11096
Authors: Vishmita Kannichamy, Ishan Antony, Vinayak Mishra, Amit Banerjee, Arohi B Gandhi, Ifrah Kaleem, Josh Alexander, Mohamed Hisbulla, Safeera Khan
Language: English
Topic: Inflammatory Bowel Disease
Subfield: Genetics
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W3094519112