A case of accidental vincristine overdose and effective use of therapeutic plasma exchange in its management
Year: 2020
Type: article
Study design: Case Report
Abstract: Vincristine is a common drug used in hematological malignancy with a maximum per dose limited to 2 mg mainly to limit neurotoxicity. Vincristine overdose and wrong route of administration, though has been reported in world literature, but its appropriate management is still undefined. We report a case of Hodgkin lymphoma being treated with adriamycin, bleomycin, vinblastine and dacarbazine protocol, where vincristine was accidently administrated instead of vinblastine due to its “look-alike, sound-alike” nature. The patient developed severe toxicity due to the same, which was effectively managed by therapeutic plasma exchange.
Authors: Hari Goyal, Anil Khetarpal, Amit Kumar Jain
Institution: Artemis Hospitals
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3094836085