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Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling

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Year: 2020
Type: article
Source: Blood
DOI: 10.1182/blood-2020-141498
Authors: Thiyagaraj Mayuranathan, Jonathan S. Yen, Gregory A. Newby, Yu Yao, Shaina N. Porter, Kaitly J. Woodard, Jingjing Zhang, Kalin Mayberry, Akshay Sharma, Shondra M. preutt-Miller, John F. Tisdale, Shengdar Q. Tsai, David R. Liu, Mitchell J. Weiss
Institutions: St. Jude Children's Research Hospital, Broad Institute, Howard Hughes Medical Institute, Harvard University, Massachusetts Institute of Technology, National Heart, Lung, and Blood Institute
Language: English

Topic: Hemoglobinopathies and Related Disorders
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W3095520077
FWCI: 1.093
Cites:
Cited by: 14
Related to: 10
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