Year: 2020
Type: review
Abstract: Eating disorders are life-interrupting psychiatric conditions with high morbidity and mortality, yet the basic mechanisms underlying these conditions are understudied compared with other psychiatric disorders. In this opinion, we suggest that recent knowledge gleaned from genomic and neuroimaging investigations of eating disorders in humans presents a rich opportunity to sharpen animal models of eating disorders and to identify neural mechanisms that contribute to the risk and maintenance of these conditions. Our article reflects the state of the science, with a primary focus on anorexia nervosa (AN) and binge-eating behavior, and encourages further study of all conditions categorized under feeding and eating disorders.
Source: Trends in Neurosciences
Authors: Sarah A. Stern, Cynthia M. Bulik
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $4,000
Awards: G103800658, G1181994271, G1375331873, Microbiome-mediated weight, anxiety, and stress dysregulation in anorexia nervosa, Eating Disorders Genetics Initiative (EDGI), G211885902, 1/7 Psychiatric Genomics Consortium: Finding actionable variation, G303339423, G3197369316, G3964009410, Predicting Binge and Purge Episodes from Passive and Active Apple Watch Data Using a Dynamical Systems Approach, G4670273794, G5012122282, Premorbid metabolism and growth in anorexia nervosa: A genetically informed exploration of risk, Neural circuit mechanisms controlling non-homeostatic feeding, Neural circuit mechanisms controlling non-homeostatic feeding, Predicting the multi-omic impact of psychiatric GWAS associations
OpenAlex ID: W3095569865