Work

Amyloid Hypothesis: The Emperor’s New Clothes?

Year: 2020

Type: article

Abstract: The lengthy debate on the validity of the amyloid hypothesis and the usefulness of amyloid imaging and anti-amyloid therapeutic interventions in dementia continues unabated, even though none of them have been able to convince the medical world of their correctness and clinical value. There are huge financial interests associated with promoting both, but in spite of the large sums of money in their support, no effective anti-amyloid treatments or diagnostic use of amyloid imaging have emerged. There are solid scientific reasons that explain these negative results, and it is time to move forward to other promising options for the benefit of the patients.

Source: Journal of Alzheimer s Disease

DOI: 10.3233/jad-200990

Authors: Poul F. Høilund-Carlsen, Jorge R. Barrio, Tom J. Werner, Andrew Newberg, Abass Alavi

Institutions: University of Southern Denmark, Odense University Hospital, University of California, Los Angeles, Hospital of the University of Pennsylvania, Thomas Jefferson University

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3095769632

FWCI: 1.055

Cites: 10

Cited by: 8

Related to: 10