Work

Author response: Arrayed CRISPRi and quantitative imaging describe the morphotypic landscape of essential mycobacterial genes

Year: 2020

Type: peer-review

Abstract: A high-throughput functional genomics approach combining inducible CRISPR-interference and quantitative imaging yields an atlas of 'phenoprints' to guide gene function assignments, identify metabolic pathway-specific morphotypes, and inform antibiotic mechanism-of-action studies.

Source: eLife

DOI: 10.7554/elife.60083.sa2

Authors: Timothy J de Wet, Kristy R Winkler, Musa Mhlanga, Valerie Mizrahi, Digby F Warner

Institutions: South African Medical Research Council, University of Cape Town, Institute of Infectious Disease and Molecular Medicine, Wellcome Centre for Infectious Diseases Research in Africa

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W3096542049

Cites:

Cited by: 1

Related to: 10