Association between consumption of dairy products and serum lipids in subjects with coronary heart disease
Year: 2013
Type: dissertation
Study design: Observational Study
Abstract: Serum lipids consist of different kinds of lipids in blood.Total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglycerides are the most important serum lipids.Hyperlipidemia is the elevated level of serum lipids which is considered as an important risk factor for cardiovascular diseases.Dairy products are one of the food groups rich in fat especially saturated fat.So many studies have been done to clarify the association between dairy products and serum lipids and heart diseases; however, varying in results shows need to more studying.A cross sectional survey was done at Kuopio University Hospital.531 subjects under 71 years old were selected from hospital discharge list.412 participants responded to studying and finally 253 patients whom did not use lipid lowering drugs were included analyses.Patients included were diagnosed with coronary artery bypass grafting, acute myocardial infarction, acute myocardial ischemia or percutaneous transluminal coronary angioplasty.Data were collected by interview (medical questionnaire) and blood sampling.Dietary intake for four days was assessed by food records.SPSS was used to analyze the statistics.Mean of TC (total cholesterol), HDL (high density lipoprotein cholesterol), LDL (low density lipoprotein cholesterol), TG (triglycerides), energy intake, energy percent (E%) from total fat, MUFA (monounsaturated fatty acids), PUFA (polyunsaturated fatty acids), SAFA (saturated fatty acids) and also ratio of TC/HDL in patients who did not use lipid lowering drugs and also in men and women separately were calculated.Concentrations of serum lipids in men were less than in women; however, TC/HDL was less in women.Energy intake (mean±SD) was reported 1852 ± 457 Kcal per day for men and 1416 ± 414 Kcal per day for women.Energy percent of total fat, PUFA and MUFA were 33.4 ± 7; 5.8 ± 1.9 and 11.4 ± 2.7, respectively which were in the recommended range (total fat: 25-35%; PUFA: 5-10%; MUFA:10-20%).Spearman correlation coefficient and P-value between dairy products consumption and serum lipids were calculated.They showed that there was no association between dairy products consumption and serum lipids levels.Participants were divided in tertiles of dairy products consumption and any differences of serum lipid levels in low, medium and high intake of different type of dairy products was investigated.The data showed no significant difference among the consumption groups of total dairy products, liquid milk, sour milk, butter or cheese.In totality, findings show, there is no association between dairy products and serum lipids in subjects who have CHD.FOREWORD For writing this master thesis I am going to present my deepest appreciate and gratitude to my principal supervisor Assistant professor, Arja Erkkilä to support and very useful guidance during long time preparing and writing this thesis and thanks for her patience as well and also for her friendly consultation.I also like to very appreciate of my second supervisor, Dr. Sohaib Khan for his useful guidance during writing thesis and in related classes and his friendly advices.I wish to thank of Professor Juhani Miettola for helping in thesis instructions and related classes, coordinators Annikä Männikkö and Paolo Kontro for their guidance, staffs in IT helpdesk department because of so many times helping to support me for soft ware and dissolving my computer problems during my thesis preparing.My very warm thanks also to my wife and my son for
Author: Amir Mowloughi
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3097546286