Work

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

Year: 2020

Type: article

Abstract: A conserved SUMO-ubiquitin-proteasome pathway protects cells from DNA damage induced by topoisomerases.

Source: Science Advances

DOI: 10.1126/sciadv.aba6290

Authors: Yilun Sun, Lisa M. Miller Jenkins, Yijun P. Su, Karin C. Nitiss, John L. Nitiss, Yves Pommier

Institutions: National Institutes of Health, University of Illinois Chicago, Rockford campus, National Cancer Institute, Center for Cancer Research, National Institute of Biomedical Imaging and Bioengineering

Language: English

Topic: Ubiquitin and proteasome pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Cancer Institute

Awards: G5705457035, G9000173957

OpenAlex ID: W3099956633

FWCI: 5.735

Cites: 90

Cited by: 148

Related to: 10