Aberrant expression of miR-16, B12 and CD272 in peripheral blood mononuclear cells from patients with active tuberculosis.
Year: 2020
Type: article
Study design: Observational Study
Abstract: monocytes was up-regulated and B12 mRNA and CD272 mRNA expressions were down-regulated in TB patients. Finally, we found that miR-16 may participate in the TB immunization process through targeted regulation of B12 expression. These studies indicate that the expression of B12, CD272 and miR-16 in PBMC may be related to tuberculosis.
Source: PubMed
Authors: Dongzi Lin, Qiankun Liu, Wei Wang, Yanyun Li, Yumei Li, Bihua Lin, Ziyu Ye, Juan Huang, Xiaolin Yu, Yinwen Chen, Yuezhi Mei, Minyuan Huang, Weiqin Yang, Jie Zhou, Xinguang Liu, Jincheng Zeng
Institution: Guangdong Medical College
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3105296441