Work

Heat therapy improves body composition and muscle function but does not affect capillary or collateral growth in a model of obesity and hindlimb ischemia

Year: 2020

Type: article

Abstract: The epidemic of obesity-related dyslipidemia and diabetes is a central cause of the increasing burden of peripheral artery disease (PAD), but few accessible therapies exist to mitigate the metabolic and functional abnormalities in these patients. We report that daily exposure to heat therapy (HT) in the form of lower-body immersion in water heated to 39 °C for 3 weeks attenuates fat accumulation and weight gain, and improves muscle strength in obese mice with femoral artery occlusion.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00535.2020

Authors: Kyoungrae Kim, Bohyun Ro, Frederick W. Damen, Daniel P. Gramling, Trevor D. Lehr, Qifan Song, Craig J. Goergen, Bruno T. Roseguini

Institution: Purdue University West Lafayette

Language: English

Topic: Thermoregulation and physiological responses

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: American Heart Association, Indiana Clinical and Translational Sciences Institute, Ralph W. and Grace M. Showalter Research Trust Fund, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Heat therapy for Intermittent Claudication, G1658722619, Interdisciplinary Bioengineering Training in Diabetes Research, Spatial Analysis of Cardiac Disease using Murine Four-Dimensional Ultrasound, G3379153675, G3981666041, G6037464466

OpenAlex ID: W3105954695

FWCI: 0.751

Cites: 79

Cited by: 11

Related to: 10