Histopatologis Hepar Ayam Petelur Yang Diinfeksi Avian Pathogenic Escherichia Coli (Apec) Setelah Diberi Kombinasi Ekstrak Sambiloto (Andrographis Paniculata Nees.)Dan Meniran (Phyllanthus Niruni Linn.)
Year: 2020
Type: dissertation
Abstract: The purpose of the research is to know combination of meniran extract \n(Phyllanthus niruri Linn.) and sambiloto extract (Andrographis paniculata Nees.) to \nthe histopatological liver layer of chicken infected with APEC (Avian Pathogenic \nEscherichia coli). This research used twenty four of thirty two weeks old layer hens, \ndivided into six treatment groups, each of group contain of four layer hens. Treatment \ngroups consists of P(-) (suspension of CMC Na 0.5% + aquadest), P(+) (Suspension \nof CMC Na 0.5% + E. coli bacteria with concentration 108 CFU/ml/kgBW), \nP(Exract) (combination of meniran extract (Phyllanthus niruri Linn.) with 20% \nconcentration and sambiloto extract (Andrographis paniculata Nees.) with 20% \nconcentration + aquadest), P1, P2, and P3 (each of group given with meniran extract \n(Phyllanthus niruri Linn.) and sambiloto extract (Andrographis paniculata Nees.) \n30% and 10%, 20% and 20%, also 10% and 30% + E. coli bacteria with 108 \nCFU/ml/kgBW concentration). Observation with hepatocyte cell necrosis, \ndegeneration of hepatocyte cell and inflamation portals. Data analysis was performed \nwith the kruskall-wallis test and continued with the mann-whitney test. This research \nshowed significant difference (p<0.05) between each treatment group. The \nconclusion of this research showed that combination meniran extract (Phyllanthus \nniruri Linn.) and sambiloto extract (Andrographis paniculata Nees.) can effect the \nliver histopatology with the best combination to reduce the level demage due to \nAPEC infection is 20% : 20%.
Author: Muhammad Rif’at Akhsan
Language: Indonesian
Subfield: Animal Science and Zoology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3108871655