Work

Targeting drug transporters to prevent chemotherapy-induced peripheral neuropathy

Year: 2020

Type: editorial

Abstract: Chemotherapy-induced peripheral neuropathy is a debilitating toxicity that adversely affects patient quality and course of treatment. Recent findings have demonstrated that the etiology of peripheral neuropathy is dependent on transporter-mediated accumulation in dorsal root ganglia, and targeting this mechanism can afford neurological protection without compromising therapeutic efficacy.

Source: Molecular & Cellular Oncology

DOI: 10.1080/23723556.2020.1838863

Authors: Kevin M. Huang, Shuiying Hu

Institution: The Ohio State University

Language: English

Topic: Cancer Treatment and Pharmacology

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Foundation for the National Institutes of Health, National Cancer Institute