Work

Pervasive cis effects of variation in copy number of large tandem repeats on local DNA methylation and gene expression

Year: 2021

Type: article

Study design: Observational Study

Source: The American Journal of Human Genetics

DOI: 10.1016/j.ajhg.2021.03.016

Authors: Paras Garg, Alejandro Martin-Trujillo, Oscar L. Rodriguez, Scott J. Gies, Elina Hadelia, Bharati Jadhav, Miten Jain, Benedict Paten, Andrew J. Sharp

Institutions: Icahn School of Medicine at Mount Sinai, University of California, Santa Cruz

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: American Heart Association, Icahn School of Medicine at Mount Sinai, National Institutes of Health, National Human Genome Research Institute, NIH Office of the Director, National Institute of Neurological Disorders and Stroke, Common Fund

Awards: G1696708022, Identification of novel pathogenic tandem repeat expansions using long read sequencing, Transforming Genomics with 5 PB Big Omics Data Engine Cray CS300-AC Supercomputer, Enabling Comparative Pangenomics, G5407203003, Identification of novel pathogenic tandem repeat expansions using long read sequencing, Development and application of a pipeline to identify tandem repeat expansions as a cause of Parkinson's disease in the AMP PD cohort, G861748693, GENCODE: comprehensive gene annotation for human and mouse

OpenAlex ID: W3146264493

FWCI: 4.378

Cites: 65

Cited by: 36

Related to: 10