Work

In-silico pharmacophoric and molecular docking-based drug discovery against the Main Protease (Mpro) of SARS-CoV-2, a causative agent COVID-19

Year: 2020

Type: article

Abstract: of SARS-CoV-2 and strong inhibition effect than the N3 (reference inhibitor). A good binding energy, drug likeness and effective pharmacokinetic parameters suggest that these candidates have greater potential to stop the replication of SARS-CoV-2, hence might lead to the cure of COVID-19.

Source: Pakistan Journal of Pharmaceutical Sciences

DOI: 10.36721/pjps.2020.33.6.reg.2697-2705.1

Authors: Zeshan Haider, Muhammad Muneeb Subhani, Muhammad Ansar Farooq, Maryum Ishaq, Maryam Khalid, Muhammad Numan Akram, Rao Sohail Ahmad Khan, Adnan Khan Niazi

Institutions: University of Agriculture Faisalabad, Fauji Fertilizer (Pakistan), Allied Hospital

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4251296810

FWCI: 0.435

Cites:

Cited by: 8

Related to: 10