Work

Uniform spatial pooling explains topographic organization and deviation from receptive-field scale invariance in primate V1

Year: 2020

Type: article

Abstract: Receptive field (RF) size and preferred spatial frequency (SF) vary greatly across the primary visual cortex (V1), increasing in a scale invariant fashion with eccentricity. Recent studies reveal that preferred SF also forms a fine-scale periodic map. A fundamental open question is how local variability in preferred SF is tied to the overall spatial RF. Here, we use two-photon imaging to simultaneously measure maps of RF size, phase selectivity, SF bandwidth, and orientation bandwidth-all of which were found to be topographically organized and correlate with preferred SF. Each of these newly characterized inter-map relationships strongly deviate from scale invariance, yet reveal a common motif-they are all accounted for by a model with uniform spatial pooling from scale invariant inputs. Our results and model provide novel and quantitative understanding of the output from V1 to downstream circuits.

Source: Nature Communications

DOI: 10.1038/s41467-020-19954-9

Authors: Y. Chen, H. Ko, B. V. Zemelman, E. Seidemann, I. Nauhaus

Institution: The University of Texas at Austin

Language: English

Topic: Visual perception and processing mechanisms

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,380

Funders: National Institutes of Health, National Eye Institute, National Institute of Neurological Disorders and Stroke