Work

Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling

Year: 2020

Type: article

Abstract: cell numbers, suggesting that it may be a therapeutic target to promote immune tolerance.

Source: Science Signaling

DOI: 10.1126/scisignal.abb0619

Authors: Suresh K. Mendu, Marta E. Stremska, Michael S. Schappe, Emily K. Moser, Julia K. Krupa, Jason S. Rogers, Eric J. Stipes, Clare A. Parker, Thomas J. Braciale, Justin S. A. Perry, Bimal N. Desai

Institutions: University of Virginia, Howard Hughes Medical Institute, Harvard University, University of Florida, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences

Awards: TRPM7 at the Crossroads of Tissue Homeostasis and inflammation, G5331955369, Training in the Pharmacological Sciences, Cancer Center Support Grant

OpenAlex ID: W3111975815

FWCI: 0.962

Cites: 53

Cited by: 21

Related to: 10