Work

In Vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-Emergent Resistance to Ceftolozane-Tazobactam

Year: 2021

Type: article

Abstract: We compared the in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates collected before and after treatment-emergent resistance to ceftolozane-tazobactam. Median baseline and postexposure ceftolozane-tazobactam MICs were 2 and 64 μg/ml, respectively.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00084-21

Authors: Abigail M. Rubio, Ellen G. Kline, Chelsea E. Jones, Liang Chen, Barry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy, Vaughn S. Cooper, Ghady Haidar, Daria Van Tyne, Ryan K. Shields

Institutions: University of Pittsburgh, Hackensack Meridian Health, Hackensack Meridian School of Medicine, University of Pittsburgh Medical Center, VA Pittsburgh Healthcare System

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences

Awards: G118719416, G1625661133, G3403622360, The molecular basis of the carbapenem resistance epidemic, G3537838402, G5346124413, G5773025019, Predicting the emergence of antibiotic resistance through multi-omics approaches and Immune System-surveillan, G8701759666, Institutional Career Development Core, G993140693

OpenAlex ID: W3112147994

FWCI: 3.084

Cites: 33

Cited by: 64

Related to: 10