Work

Optogenetics: The Art of Illuminating Complex Signaling Pathways

Year: 2020

Type: article

Abstract: Dissection of cell signaling requires tools that can mimic spatiotemporal dynamics of individual pathways in living cells. Optogenetic methods enable manipulation of signaling processes with precise timing and local control. In this review, we describe recent optogenetic approaches for regulation of cell signaling, highlight their advantages and limitations, and discuss examples of their application.

Source: Physiology

DOI: 10.1152/physiol.00022.2020

Authors: Mark Shaaya, Jordan Fauser, Andrei V. Karginov

Institution: University of Illinois Chicago

Language: English

Topic: Photoreceptor and optogenetics research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

Funders: Chicago Biomedical Consortium, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences