Work

Urinary ezrin and moesin as novel markers for recovery from acute kidney injury

Year: 2020

Type: article

Abstract: Acute kidney injury (AKI) is a common disorder associated with high morbidity and mortality among critically ill patients. Approximately 5% of all patients admitted to intensive care units around the world develop severe AKI requiring dialysis [1]. Currently there is no effective treatment to facilitate renal recovery in patients with AKI. The ability to forecast renal recovery is extremely valuable since it will provide physicians with an insight to optimize utilization of renal replacement therapy (RRT) and appropriate follow-up timing for these patients. Although the mechanisms of renal recovery are still incompletely understood, several processes, including cellular dedifferentiation, cellular proliferation and epithelialization, are thought to be key steps in recovery after...

Source: Nephrology Dialysis Transplantation

DOI: 10.1093/ndt/gfaa328