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A Multi-Mode System for Myocardial Functional and Physiological Assessment during Ex Situ Heart Perfusion.

Year: 2020

Type: article

Abstract: = .942, at 2 and 4 hours, respectively). The present study proposed a novel ESHP system that enables comprehensive functional and metabolic assessment of large mammalian hearts. This system allowed for stable myocardial function for up to 4 hours of perfusion, which would offer great potential for the development of translational therapeutic protocols to improve dysfunctional donated hearts.

Source: PubMed Central

DOI: 10.1182/ject-2000034

Authors: Thomas Duignan, Alvise Guariento, Ilias P Doulamis, Takashi Kido, William L Regan, Mossab Saeed, David M Hoganson, Sitaram M Emani, Pedro J Del Nido, James D McCully, Gregory S Matte

Institutions: Boston Children's Hospital, Harvard University

Language: English

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3115921495

FWCI: 0.228

Cites: 24

Cited by: 3

Related to: 10