Work

High Fructose Drives the Serine Synthesis Pathway in Acute Myeloid Leukemic Cells

Year: 2020

Type: article

Source: Cell Metabolism

DOI: 10.1016/j.cmet.2020.12.005

Authors: Sangmoo Jeong, Angela Maria Savino, Rachel Chirayil, Ersilia Barin, Yuanming Cheng, Sun-Mi Park, Alexandra Schurer, Edouard Mullarky, Lewis C. Cantley, Michael G. Kharas, Kayvan R. Keshari

Institutions: Memorial Sloan Kettering Cancer Center, Cornell University, Weill Cornell Medicine

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Alex's Lemonade Stand Foundation for Childhood Cancer, Memorial Sloan-Kettering Cancer Center, National Institutes of Health, Weill Cornell Medical College, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Identification of therapeutic targets for leukemia stem cells in AML-iPSC models, G289723095, Molecular and genetic analysis of novel Slicer-dependent miRNA pathways in blood, Visualizing oxidative stress using hyperpolarized magnetic resonance, uCoil NMR platform for robust and high-throughput analysis of in vitro metabolic flux on living cells, Uncovering the role for MSI2 network in hematopoietic stem cells, Development of large-field-of-view hyperpolarized MRI, Hyperpolarized Micro-NMR for Quantitative Analysis of Metabolism in Leukemia Stem Cells, Cancer Center Support Grant, Role of Phosphoinositides and Protein Kinases in the control of Cancer Metabolism, Characterizing the MSI2 network in leukemia

OpenAlex ID: W3116380899

FWCI: 3.258

Cites: 59

Cited by: 76

Related to: 10